About 75,000 Canadians are occupationally exposed to antineoplastic agents. The largest occupational group are pharmacy staff including pharmacists, technicians and assistants according to the Carex. With changes driven by USP General Chapter <800> Hazardous Drugs—Handling in Healthcare Settings and NAPRA guidance.
This exposure is putting them at risk of both short- and long-term health issues such as headaches, hair loss, nausea, organ damage, reproductive problems,2 developmental impairment, genetic issues and even cancer.3
To address these risks, healthcare facilities need to comply with new and existing standards, guidelines and recommendations. With changes driven by USP General Chapter <800> Hazardous Drugs—Handling in Healthcare Settings, facilities should use a closed system drug transfer device (CSTD) when compounding hazardous drugs when the dosage form allows, and CSTDs must be used when administering antineoplastic hazardous drugs when the dosage form allows.4