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Phasix™ ST Mesh

Fully Bioresorbable Scaffold Featuring Proven Sepra® Technology

Phasix-ST
PF10136_Phasix-ST_Hiatal
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Overview

Features and Benefits

MATERIAL STRUCTURE1

Monofilament mesh designs have been shown more biocompatible and less susceptible to bacterial adherence and colonization.

REPAIRS HERNIAS1

The open monofilament mesh structure provides early integration and repair strength.1

REMODELS ISSUES OVER TIME1

Vascular integration and incorporation continues, with abundant mature collagen at 52 weeks. Gradually transfers load to native tissue over time.1

VERSATILE TECGNIQUES1

Phasix™ ST Mesh may be placed in either an intraabdominal or preperitoneal position after primary hernia defect closure. Primary hernia defect closure should be achieved prior to placing the mesh.

HERNIA DEFECT CLOSURE

Hernia defect closure can be achieved through an open or minimally invasive approach (i.e., laparoscopic, robotic). Recent studies suggest potential advantages of defect closure include:

• Decreased “dead” space, which can reduce the risk of postoperative seromas

• May contribute to restoration of a functional abdominal wall

• May reduce postoperative bulging at the hernia defect site

PROMISING RESULTS IN THE PRESENCE OF BACTERIA

Phasix™ ST Mesh has not been shown to break down in the presence of bacteria—maintaining 100% of its strength at 56 days —unlike biologic grafts which demonstrate accelerated degradation in the presence of bacteria.

As shown in the graphic below, there was no presence of bacterial colonization observed in Phasix™ Mesh or Phasix™ ST Mesh 7 days post-inoculation in preclinical testing. The other side of this graph shows the presence of abscess (white material) observed SurgiMend® , Strattice™, Bio - A®, and OviTex™. Other observed indications of bacterial colonization included swelling, presence of fluids, and thickened capsule tissue.

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BD-76012

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